Chimerism Whole Bone Marrow Biopsy
DAY +28 04/03/2013 100% donor Noa 0% Liam 0% donor Hunter
DAY +84 05/29/2013 79% donor Noa 21% Liam 0% donor Hunter
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DNA Sorted Chimerism Peripheral Blood
(CD3+) T Cell, (CD33+) Myeloid Cells, (CD56+) NK Cells, (CD19+) B Cells
DAY +28 – APRIL 03, 2013
DNA Sorted Chimerism CD3+ CD33+ CD56+ CD19+
DAY +28 (NOA CELLS) 42% 100% 48% 90%
DAY +28 (Hunter’s Cells) 16% 0% 0% 0%
DAY +28 (LIAM’S CELLS) 42% 0% 52% 10%
DAY +42 – APRIL 17, 2013
DNA Sorted Chimerism CD3+ CD33+ CD56+ CD19+
DAY +42 (NOA CELLS) 41% 100% 50% N/T
DAY +42 (Hunter’s Cells) 10% 0% 0% N/T
DAY +42 (LIAM’S CELLS) 49% 0% 50% N/T
*N/T = NOT TESTED
DAY +84 – MAY 29, 2013
DNA Sorted Chimerism CD3+ CD33+ CD56+ CD19+
DAY +84 (NOA CELLS) 52% 87% 69% 93%
DAY +84 (Hunter’s Cells) 4% 0% 0% 0%
DAY +84 (LIAM’S CELLS) 44% 13% 31% 7%
DAY +114 – June 28, 2013
DNA Sorted Chimerism CD3+ CD33+ CD56+
DAY +114 (NOA’s Cells) 57% N/T 75%
DAY +127 – July 11, 2013
DNA Sorted Chimerism CD3+ CD33+ CD56+
DAY +127 (NOA’s Cells) 57% 78% 71%
DAY +156 – August 8, 2013
DNA Sorted Chimerism CD3+ CD33+ CD56+
DAY +156 (NOA’s Cells) 63% 71% 74%
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Chimerism Whole Peripheral Blood – % OF NOA’S CELLS
04/23/13 85%
05/03/13 94%
05/10/13 81%
05/17/13 77%
05/29/13 79%
