LIAM’S CHIMERISM TEST RESULTS 2nd BMT – DAY +28, +42, +84, +114, +127, +156

Chimerism Whole Bone Marrow Biopsy

DAY +28     04/03/2013     100% donor Noa     0% Liam     0% donor Hunter

DAY +84     05/29/2013     79% donor Noa       21% Liam   0% donor Hunter

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DNA Sorted Chimerism Peripheral Blood

(CD3+) T Cell, (CD33+) Myeloid Cells, (CD56+) NK Cells, (CD19+) B Cells

DAY +28 – APRIL 03, 2013

DNA Sorted Chimerism      CD3+  CD33+    CD56+    CD19+

DAY +28 (NOA CELLS)       42%    100%     48%       90%

DAY +28 (Hunter’s Cells)   16%      0%        0%        0%

DAY +28 (LIAM’S CELLS)   42%      0%       52%       10%

 DAY +42 – APRIL 17, 2013

DNA Sorted Chimerism      CD3+    CD33+    CD56+    CD19+

DAY +42 (NOA CELLS)      41%     100%      50%       N/T

DAY +42 (Hunter’s Cells)   10%     0%          0%        N/T

DAY +42 (LIAM’S CELLS)   49%     0%         50%       N/T

*N/T = NOT TESTED

DAY +84 – MAY 29, 2013

DNA Sorted Chimerism      CD3+   CD33+    CD56+   CD19+

DAY +84 (NOA CELLS)      52%     87%        69%      93%

DAY +84 (Hunter’s Cells)   4%      0%          0%        0%

DAY +84 (LIAM’S CELLS)   44%    13%        31%       7%

DAY +114 – June 28, 2013

DNA Sorted Chimerism      CD3+    CD33+    CD56+

DAY +114 (NOA’s Cells)     57%     N/T       75%

DAY +127 – July 11, 2013

DNA Sorted Chimerism      CD3+   CD33+    CD56+

DAY +127 (NOA’s Cells)     57%     78%       71%

DAY +156 – August 8, 2013

DNA Sorted Chimerism      CD3+   CD33+    CD56+

DAY +156 (NOA’s Cells)     63%     71%       74%

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Chimerism Whole Peripheral Blood – % OF NOA’S CELLS

04/23/13      85%

05/03/13      94%

05/10/13     81%

05/17/13     77%

05/29/13     79%

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